Some US proof sets can be worth quite a bit. For example, those made between 1947 and 1953 that are still in their original packaging can be worth $1000 or more.
Generally speaking, unless damaged, your US proof set should be of some interest to our collectors.
For more information on what a particular US mint proof set value is, please see our free appraisal page. From there, just submit an inventory list and you can receive a quick, risk-free appraisal.